The GeoMx platform allows for the profiling of gene expression in-situ, meaning that gene expression can be analyzed directly within intact tissue sections. This is accomplished through the integration of traditional histology methods with high-throughput molecular profiling. By utilizing a spatially resolved assay, the platform captures and measures RNA transcripts from individual cells in a tissue section.

GeoMx allows researchers to obtain insights about the spatial distribution of gene expression patterns, cellular diversity, and interactions within tissues. This technology is a useful resource for studying intricate biological mechanisms, including growth, disease advancement, and reaction to therapy.

Researchers can gain a more comprehensive understanding of cellular interactions, tissue organization and the underlying mechanisms driving disease or normal physiological processes by combining spatial transcriptomics with traditional histology. This approach enables the identification of specific cell types and regions within a tissue that are linked to particular gene expression patterns.

GeoMx is a versatile technology that finds its utility across diverse domains such as cancer research, neuroscience, immunology and developmental biology. It empowers researchers with a potent means to explore the spatial arrangement of gene expression in tissues, thereby enhancing our comprehension of intricate biological systems.